Endogenous antigens shape the transcriptome and TCR repertoire in an autoimmune arthritis model
Elizabeth McCarthy, Steven Yu, Noah Perlmutter, Yuka Nakao, Ryota Naito, Charles Lin, Vivienne Riekher, Joe DeRisi, Chun Jimmie Ye*, Arthur Weiss*, and Judith F. Ashouri*. *co-corresponding authors
Journal of Clinical Investigation, 2024.
Related Article: A new twist on superantigen-activated autoimmune disease
Andrew L. Mason, Doaa Waly, and Mohammed S. Osman
Repeated immunization with ATRA-containing liposomal adjuvant transdifferentiates Th17 cells to a Tr1-like phenotype
Katharina Wørzner*, Julie Zimmermann, Regitze Buhl, Anna Desoi, Dennis Christensen, Jes Dietrich, Nina Dieu Nhien Tran Nguyen, Thomas Lindenstrøm, Joshua S. Woodworth, Reham Sabah Alhakeem, Steven Yu, Niels Ødum, Rasmus Mortensen, Judith F. Ashouri*, Gabriel K. Pedersena. *co-corresponding authors
Journal of Autoimmunity, 2024
Hepatic Ly6CLo Non-Classical Monocytes Have Increased Nr4a1 (Nur77) in Murine Biliary Atresia
Sarah Mohamedaly, Claire S Levy, Cathrine Korsholm, Anas Alkhani, Katherine Rosenberg, Judith F Ashouri, Amar Nijagal
Journal of Clinical Medicine, 2022
ZAP70, too little, too much can lead to autoimmunity.
Ashouri JF, Lo WL, Nguyen TTT, Shen L, Weiss A
Immunologic Reviews, 2021
The Therapeutic Landscape of Rheumatoid Arthritis: Current State and Future Directions.
Shams S, Martinez JM, Dawson JRD, Flores J, Gabriel M, Garcia G, Guevara A, Murray K, Pacifici N, Vargas MV, Voelker T, Hell JW, Ashouri JF.
Frontiers in Pharmacology, 2021
Cross-Tissue Transcriptomic Analysis Leveraging Machine Learning Approaches Identifies New Biomarkers for Rheumatoid Arthritis.
Rychkov D, Neely J, Oskotsky T, Yu S, Perlmutter N, Nititham J, Carvidi A, Krueger M, Gross A, Criswell LA, Ashouri JF, Sirota M
Frontiers in Immunology, 2021
Therapeutic Implications of Diet in Inflammatory Bowel Disease and Related Immune-Mediated Inflammatory Diseases.
Jiang Y, Jarr K, Layton C, Gardner CD, Ashouri JF, Abreu MT, Sinha SR
Nutrients, 2021
Efficacy of Dietary Supplements in Inflammatory Bowel Disease and Related Autoimmune Diseases.
Jadhav P, Jiang Y, Jarr K, Layton C, Ashouri JF*, Sinha SR*. *co-corresponding authors
Nutrients, 2020
Developing Human Skin Contains Lymphocytes Demonstrating a Memory Signature.
Dhariwala MO, Karthikeyan D, Vasquez KS, Farhat S, Weckel A, Taravati K, Leitner EG, Clancy S, Pauli M, Piper ML, Cohen JN, Ashouri JF, Lowe MM, Rosenblum MD, Scharschmidt TC
Cell Reports, Medicine, 2020
Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis.
JF Ashouri, L-Y Hsu, S Yu, Y Chen, DA Cheng, E Hansen, L Lattanza, J Zikherman, A Weiss
Proc Natl Acad Sci U S A, 2019
Endogenous Nur77 is a specific indicator of antigen receptor signaling in human T and B cells.
Ashouri JF, Weiss A
Journal of Immunolology, 2017
A Sharp TCR Signaling Threshold for T cell Proliferation.
B Au-Yeung, J Zikherman, J Mueller, J Ashouri, D Cheng, Y Chen, K Shokat, and A Weiss
Proc Natl Acad Sci U S A, 2014
A Young woman with systemic lupus erythematosus and extensive mesenteric vasculitis involving small and medium vessels.
Ashouri JF, Davis JL, Farkas A, Durack JC, Ramachandran R, Dall'Era M
Arthitis Care & Research, 2012
Rheumatic Manifestations of Cancer.
Ashouri JF, Daikh DI
Rheum Dis Clin N Am, 2011
Transcriptional regulation of EGR-1 by the interleukin-1-JNK-MKK7-c-Jun pathway.
Hoffmann E*, Ashouri J*, Wolter S*, Doerrie A, Dittrich-Breiholz O, Schneider H, Wagner E, Troppmair J, Mackman N, Kracht M. *contributed equally
Journal of Biological Chemistry, 2008
Androgens are protective in experimental autoimmune encephalomyelitis: implications for multiple sclerosis.
Palaszynski KM, Loo KK, Ashouri JF, Liu HB, Voskuhl RR.
Journal of Neuroimmunolology, 2004
Estrogen receptor alpha mediates estrogen's immune protection in autoimmune disease.
Liu HB, Loo KK, Palaszynski K, Ashouri J, Lubahn DB, Voskuhl RR.
Journal of Immunology, 2003